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Pulmonary Hypertension in Adult Congenital Heart Disease.
- Source :
- Current Treatment Options in Cardiovascular Medicine; Aug2014, Vol. 16 Issue 8, p1-12, 12p
- Publication Year :
- 2014
-
Abstract
- There is a growing patient population with adult congenital heart disease that needs specialized medical attention and careful long-term evaluation. Pulmonary arterial hypertension (PAH) associated with congenital heart disease (PAH-CHD) is a common late complication, and is associated with increased morbidity and mortality. There are no clear current guidelines for the treatment of PAH-CHD. There are few trials to date investigating PAH treatment specifically in this group of patients. However, the available data seems to demonstrate that with the advent of PAH-targeted therapies, the quality of life, exercise capacity, and outcomes in these patients is improving. In addition, PAH-targeted therapies may be useful in select patients for a combined medical-surgical approach to treatment. Here we discuss the epidemiology and pathophysiology of PAH-CHD, current therapies, and the data supporting their use, and how to evaluate feasibility of late surgical repair. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10928464
- Volume :
- 16
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Current Treatment Options in Cardiovascular Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 97287213
- Full Text :
- https://doi.org/10.1007/s11936-014-0328-z