Synthetic Studies Toward Harringtonolide.

An efficient synthesis of an oxo-bridged 7/6-bicyclic precursor that is potentially useful for the construction of harringtonolide has been realized through a [4+3] cycloaddition reaction. Meanwhile, an unexpected rearrangement reaction, which could be used for the fast assembly of spirocycles, was found during the double elimination attempts. [ABSTRACT FROM AUTHOR]