Back to Search
Start Over
Genome sequence of a 45,000-year-old modern human from western Siberia.
- Source :
- Nature; 10/23/2014, Vol. 514 Issue 7523, p445-449, 5p
- Publication Year :
- 2014
-
Abstract
- We present the high-quality genome sequence of a ∼45,000-year-old modern human male from Siberia. This individual derives from a population that lived before-or simultaneously with-the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians. However, the genomic segments of Neanderthal ancestry are substantially longer than those observed in present-day individuals, indicating that Neanderthal gene flow into the ancestors of this individual occurred 7,000-13,000 years before he lived. We estimate an autosomal mutation rate of 0.4 × 10<superscript>−9</superscript> to 0.6 × 10<superscript>−9</superscript> per site per year, a Y chromosomal mutation rate of 0.7 × 10<superscript>−9</superscript> to 0.9 × 10<superscript>−9</superscript> per site per year based on the additional substitutions that have occurred in present-day non-Africans compared to this genome, and a mitochondrial mutation rate of 1.8 × 10<superscript>−8</superscript> to 3.2 × 10<superscript>−8</superscript> per site per year based on the age of the bone. [ABSTRACT FROM AUTHOR]
- Subjects :
- GENOMES
DNA
NEANDERTHALS
GENETIC mutation
UPPER Paleolithic Period
Subjects
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 514
- Issue :
- 7523
- Database :
- Complementary Index
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- 99074324
- Full Text :
- https://doi.org/10.1038/nature13810