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Breast cancer statistics and markers.
- Source :
- Journal of Cancer Research & Therapeutics; Jul-Sep2014, Vol. 10 Issue 3, p506-511, 6p
- Publication Year :
- 2014
-
Abstract
- Breast cancer is one of the familiar diseases in women. Incidence and mortality due to cancer, particularly breast cancer has been increasing for last 50 years, even though there is a lacuna in the diagnosis of breast cancer at early stages. According to World Health Organization (WHO) 2012 reports, breast cancer is the leading cause of death in women, accounting 23% of all cancer deaths. In Asia, one in every three women faces the risk of breast cancer in their lifetime as per reports of WHO 2012. Here, the review is been focused on different breast cancer markers, that is, tissue markers (hormone receptors, human epidermal growth factor-2, urokinase plasminogen activator, plasminogen activator inhibitor, p53 and cathepsin D), genetic markers (BRAC1 and 2 and gene expression microarray technique, etc.), and serum markers (CA 15.3, BR 27.29, MCA, CA 549, carcinoembryonic antigen, oncoproteins, and cytokeratins) used in present diagnosis, but none of the mentioned markers can diagnose breast cancer at an early stage. There is a disquieting need for the identification of best diagnosing marker, which can be able to diagnose even in early stage of breast carcinogenesis. [ABSTRACT FROM AUTHOR]
- Subjects :
- BREAST cancer statistics
TUMOR markers
DISEASES in women
CANCER-related mortality
Subjects
Details
- Language :
- English
- ISSN :
- 09731482
- Volume :
- 10
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Cancer Research & Therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 99149958
- Full Text :
- https://doi.org/10.4103/0973-1482.137927