Comparison of recurrent rate of gingival pigmentation after treatment by liquid nitrogen and cryoprob in 18 months follows-up.

Background: Cryosurgery is one of the simplest, most effective gingival depigmentation methods.Repigmentation may happen after a while in each method. The aim of this study is to compare the recurrence rate after treatment by liquid nitrogen swap and a cryoprob in 18 months.Materials and Methods: A total of 26 patients with physiologic gingival pigmentation were selected.The anterior sextant was divided into left and right segments; each segment was treated random lyby swap technique or cryoprob. Standard photos were evaluated with photoshop software (Red,Green, Blue, Cyan, Magenta, Yellow, Black [RGB, CMYK]) before and at 2 week, 1, 3, 6, 9, 12, 15,18 months after the treatment. The results were compared, by the independent t-test and repeated measure ANOVA thereafter least signifi cant difference post-hoc. The viewpoints of patients and physicians regarding the treatment outcomes were obtained by a questionnaire and consequentlyevaluated qualitatively by McNemar test (P < 0.05 was considered as significant level).Results: The statistical analysis showed a significant difference in color change after the treatment during 18 months, in each group (P < 0.001). The mean values of RGB had significantly increased after 2 weeks in both methods (P < 0.001), but the differences from 2 weeks to 18 months after treatment were not significant (P > 0.05). The mean values of CMYK significantly decreased after2 weeks in both methods (P < 0.001), but the differences from 2 weeks to 18 months after treatment were not significant (P > 0.05). Qualitative evaluation showed the preference of the cryosurgery with swap method (P < 0.001). No significant recurrence was observed during 18 months follow-up.Conclusion: Both methods of cryosurgery are appropriate in treatment of gingival depigmentation because no significant recurrence was observed during 18 months follow-up. [ABSTRACT FROM AUTHOR]