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Can ends justify the means?: Telomeres and the mechanisms of replicative senescence and...

Authors :
Sedivy, John M.
Klein, George
Source :
Proceedings of the National Academy of Sciences of the United States of America; 08/04/98, Vol. 95 Issue 16, p9079, 4p
Publication Year :
1998

Abstract

Focuses on limited replicative capacity, with emphasis on the discovery of molecular insights in genes that regulate senescence. Difference between senescence and quiescence; Dominance of senescence; Information on the proliferative decline of cultures at the end of the extended lifespan phase of human cells.

Subjects

Subjects :
TELOMERES
AGING
HUMAN cell culture

Details

Language :
English
ISSN :
00278424
Volume :
95
Issue :
16
Database :
Complementary Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
997402
Full Text :
https://doi.org/10.1073/pnas.95.16.9078