Immunohistochemical expression of osteopontin in canine and feline tumors.

The article discusses a study to assess the immunohistochemical expression of osteopontin (OPN) in different canine and feline tumors and to examine any possible relation with malignancy. Topics discussed include role of OPN in cell adhesion, tumorigenesis, and metastasis of different human tumors, efforts for detection and diagnosis of early stage of cancers in humans, and contribution of OPN in breast cancer.