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Association of Prostate Cancer Risk Variants with Gene Expression in Normal and Tumor Tissue.

Authors :
Penney, Kathryn L.
Sinnott, Jennifer A.
Tyekucheva, Svitlana
Gerke, Travis
Shui, Irene M.
Kraft, Peter
Sesso, Howard D.
Freedman, Matthew L.
Loda, Massimo
Mucci, Lorelei A.
Stampfer, Meir J.
Source :
Cancer Epidemiology, Biomarkers & Prevention; Jan2015, Vol. 24 Issue 1, p255-260, 6p
Publication Year :
2015

Abstract

The article presents research on association of prostate cancer risk variants with gene expression in normal and tumor tissue. It mentions the generation of messenger ribonucleic acid (mRNA) expression data with the Affymetrix GeneChip Human Gene 1.0 ST microarray of the Physicians' Health Study and Health Professionals Follow-up Study participants. It concludes the association of risk variants with several genes of prostate cancer and lipid metabolism pathways.

Details

Language :
English
ISSN :
10559965
Volume :
24
Issue :
1
Database :
Supplemental Index
Journal :
Cancer Epidemiology, Biomarkers & Prevention
Publication Type :
Academic Journal
Accession number :
103395724
Full Text :
https://doi.org/10.1158/1055-9965.EPI-14-0694-T