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Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolinesas Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2)Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolinesas Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2)Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.
- Source :
- Journal of Medicinal Chemistry; Oct2015, Vol. 58 Issue 20, p8054-8065, 12p
- Publication Year :
- 2015
Details
- Language :
- English
- ISSN :
- 00222623
- Volume :
- 58
- Issue :
- 20
- Database :
- Supplemental Index
- Journal :
- Journal of Medicinal Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 110517120
- Full Text :
- https://doi.org/10.1021/acs.jmedchem.5b00851