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Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolinesas Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2)Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.

Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolinesas Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2)Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.

Details

Language :
English
ISSN :
00222623
Volume :
58
Issue :
20
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
110517120
Full Text :
https://doi.org/10.1021/acs.jmedchem.5b00851