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70-kVp High-pitch Computed Tomography Pulmonary Angiography with 40 mL Contrast Agent: Initial Experience.

Authors :
Li, Xie
Ni, Qian Qian
Schoepf, U. Joseph
Wichmann, Julian L.
Felmly, Lloyd M.
Qi, Li
Kong, Xiang
Zhou, Chang Sheng
Luo, Song
Zhang, Long Jiang
Lu, Guang Ming
Source :
Academic Radiology; Dec2015, Vol. 22 Issue 12, p1562-1570, 9p
Publication Year :
2015

Abstract

<bold>Rationale and Objectives: </bold>To assess image quality, radiation dose, and diagnostic accuracy of 70-kVp high-pitch computed tomography pulmonary angiography (CTPA) using 40 mL contrast agent and sinogram affirmed iterative reconstruction (SAFIRE) compared to 100-kVp CTPA using 60 mL contrast agent and filtered back projection. <bold>Materials and Methods: </bold>Eighty patients underwent CTPA at either 70 kVp (group A, n = 40; 3.2 pitch, 40 mL contrast medium, and SAFIRE) or 100 kVp (group B, n = 40; 1.2 pitch, 60 mL contrast medium, and filtered back projection). Signal-to-noise ratio and contrast-to-noise ratio were calculated. Subjective image quality was evaluated using a five-grade scale, and diagnostic accuracy was assessed. Radiation doses were compared. <bold>Results: </bold>Computed tomography values, signal-to-noise ratio, and contrast-to-noise ratio of pulmonary arteries were higher in group A compared to group B (all P < 0.001). Subjective image quality showed no difference between the two groups (P = 0.559) with good interobserver agreement (κ = 0.647). No difference was found regarding diagnostic accuracy between the two groups (P > 0.05). The effective dose for group A was lower by 80% compared to group B (P < 0.001). <bold>Conclusions: </bold>70-kVp high-pitch CTPA with reduced contrast media and SAFIRE provides comparable image quality and substantial radiation dose savings compared to a routine CTPA protocol. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10766332
Volume :
22
Issue :
12
Database :
Supplemental Index
Journal :
Academic Radiology
Publication Type :
Academic Journal
Accession number :
110681937
Full Text :
https://doi.org/10.1016/j.acra.2015.08.026