Neuroleptic malignant syndrome induced by hiccough therapy, a case report and literature review.

we report an unusual case of a patient who presented with neuroleptic malignant syndrome (NMS) associated with hiccough therapy, together with a review of the current knowledge on NMS. A 70-year-old male patient rapidly developed significant hyperthermia, rigidity, and unconsciousness and upregulated serum creatine kinase after 3 days of receiving a parenteral high dose of haloperidol. The diagnosis of NMS was established, discontinued haloperidol and dantrolene administration via nasogastric tube made him rehabilitation. which makes the clinicians be vigilant of the utilization of haloperidol and other antipsychotics, especially for non-psychosis use. [ABSTRACT FROM AUTHOR]