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Perinatal arterial ischemic stroke related to carotid artery occlusion.
- Source :
- European Journal of Paediatric Neurology; Jul2016, Vol. 20 Issue 4, p639-648, 10p
- Publication Year :
- 2016
-
Abstract
- Background The aetiology of perinatal arterial ischemic stroke remains speculative. It is however widely accepted that the aetiology is multifactorial, involving various maternal, placental, foetal and neonatal risk factors. A resulting thromboembolic process is hypothesized and the placenta identified as the most plausible source. An arteriopathy, as observed in a significant proportion of childhood ischemic stroke, is thought to be rare. Methods We report here five cases of perinatal stroke that differ from the vast majority by documented carotid occlusion, and add eleven other similar cases from the literature. Results In the majority, an intraluminal thrombus of placental origin is the most probable hypothesis, while in the remaining ones, one can reasonably presume a direct vessel wall injury related to a traumatic delivery, yet generally unproven by imaging. Conclusion We hypothesize that most of these cases share similar pathophysiology with the more common perinatal arterial ischemic stroke but differ by a persistent identified thrombus in the carotid artery at the time of first imaging, leading to a more severe and extended ischemic damage responsible for an adverse neurological outcome. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10903798
- Volume :
- 20
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- European Journal of Paediatric Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 115825501
- Full Text :
- https://doi.org/10.1016/j.ejpn.2016.03.003