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Optimization and evaluation of multiple gating beam delivery in a synchrotron-based proton beam scanning system using a real-time imaging technique.
- Source :
- Physica Medica; Jul2016, Vol. 32 Issue 7, p932-937, 6p
- Publication Year :
- 2016
-
Abstract
- Purpose To find the optimum parameter of a new beam control function installed in a synchrotron-based proton therapy system. Methods A function enabling multiple gated irradiation in the flat top phase has been installed in a real-time-image gated proton beam therapy (RGPT) system. This function is realized by a waiting timer that monitors the elapsed time from the last gate-off signal in the flat top phase. The gated irradiation efficiency depends on the timer value, T w . To find the optimum T w value, gated irradiation efficiency was evaluated for each configurable T w value. 271 gate signal data sets from 58 patients were used for the simulation. Results The highest mean efficiency 0.52 was obtained in T W = 0.2 s. The irradiation efficiency was approximately 21% higher than at T W = 0 s, which corresponds to ordinary synchrotron operation. The irradiation efficiency was improved in 154 (57%) of the 271 cases. The irradiation efficiency was reduced in 117 cases because the T W value was insufficient or the function introduced an unutilized wait time for the next gate-on signal in the flat top phase. In the actual treatment of a patient with a hepatic tumor at T w = 0.2 s, 4.48 GyE irradiation was completed within 250 s. In contrast, the treatment time of ordinary synchrotron operation was estimated to be 420 s. Conclusions The results suggest that the multiple gated-irradiation function has potential to improve the gated irradiation efficiency and to reduce the treatment time. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 11201797
- Volume :
- 32
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Physica Medica
- Publication Type :
- Academic Journal
- Accession number :
- 116863364
- Full Text :
- https://doi.org/10.1016/j.ejmp.2016.06.002