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Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A2A Adenosine Receptor Inverse Agonists with Antinociceptive Activity.

Authors :
Varano, Flavia
Catarzi, Daniela
Vincenzi, Fabrizio
Betti, Marco
Falsini, Matteo
Ravani, Annalisa
Borea, Pier Andrea
Colotta, Vittoria
Varani, Katia
Source :
Journal of Medicinal Chemistry; Dec2016, Vol. 59 Issue 23, p10564-10576, 13p
Publication Year :
2016

Details

Language :
English
ISSN :
00222623
Volume :
59
Issue :
23
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
120148886
Full Text :
https://doi.org/10.1021/acs.jmedchem.6b01068