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Comparison of very long-term clinical and angiographic outcomes of bare metal stent implants between patients with and without type 2 diabetes.
- Source :
- Primary Care Diabetes; Oct2017, Vol. 11 Issue 5, p445-452, 8p
- Publication Year :
- 2017
-
Abstract
- <bold>Background: </bold>Data on a large patient population regarding very long-term outcomes after bare metal stent (BMS) implantation in diabetic patients are lacking. The aim of this study was to evaluate the very long-term (8-17 years) clinical and 6-month angiographic outcomes of BMS implantations in patients with and without type 2 diabetes.<bold>Methods and Results: </bold>A total of 2391 patients (579 with and 1812 without diabetes) who received BMS implantations between November 1995 and May 2004 were enrolled from the Cardiovascular Atherosclerosis and Percutaneous TrAnsluminal INterventions (CAPTAIN) registry into this study. During a mean follow-up period of 152±53months, the diabetic patients had higher rates of all-cause mortality (28% vs. 15%, p<0.001), re-infarction (6% vs. 5%, p=0.284), target lesion revascularization (13% vs. 10%, p=0.049), and a lower cardiovascular event-free survival rate (42% vs. 56%, p<0.001) compared to the patients without diabetes. The diabetic patients also had a higher restenosis rate (26% vs. 18%, p<0.001) at 6-month angiographic follow-up. The multivariate analysis of risk factors for cardiac event-free survival included age (hazard ratio [HR]: 1.011; p=0.001), hypertension (HR: 1.168; p=0.011), diabetes mellitus (HR: 1.353; p<0.001), pre-existing coronary artery disease (HR: 1.341; p<0.001), and left ventricular ejection fraction (LVEF) (HR: 0.992; p=0.002) (Table 7). The Kaplan-Meier analysis showed a significant difference in cardiovascular event-free survival rate between the two groups (p<0.001).<bold>Conclusion: </bold>The clinical and angiographic outcomes of diabetic patients with BMS implantations were worse than those of patients without diabetes after a very long-term follow-up period. [ABSTRACT FROM AUTHOR]
- Subjects :
- CORONARY heart disease complications
CORONARY heart disease treatment
TYPE 2 diabetes diagnosis
MEDICAL equipment
TYPE 2 diabetes complications
CARDIOVASCULAR system
CHI-squared test
CORONARY arteries
CORONARY disease
LONGITUDINAL method
MEDICAL care
METALS
MULTIVARIATE analysis
TYPE 2 diabetes
PROGNOSIS
PROSTHETICS
SURGICAL stents
TIME
CORONARY restenosis
TREATMENT effectiveness
PREDICTIVE tests
ACQUISITION of data
PROPORTIONAL hazards models
KAPLAN-Meier estimator
CORONARY angiography
Subjects
Details
- Language :
- English
- ISSN :
- 17519918
- Volume :
- 11
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Primary Care Diabetes
- Publication Type :
- Academic Journal
- Accession number :
- 124983158
- Full Text :
- https://doi.org/10.1016/j.pcd.2017.04.006