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Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis.
- Source :
- Journal of Medicinal Chemistry; 3/5/2018, Vol. 61 Issue 5, p2027-2040, 14p
- Publication Year :
- 2018
Details
- Language :
- English
- ISSN :
- 00222623
- Volume :
- 61
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Journal of Medicinal Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 128488467
- Full Text :
- https://doi.org/10.1021/acs.jmedchem.7b01708