Postoperative amaurosis after ethmoidectomy revealing Leber's hereditary optic neuropathy.

MRI demonstrated left optic nerve atrophy with signal abnormalities extending as far as the optic chiasma. LHON is a mitochondrial disease caused by a mtDNA mutation, altering the respiratory chain and leading to selective death of retinal ganglion cells (RGC), resulting in optic nerve degeneration [2]. MRI sometimes rapidly shows a nonspecific high-intensity signal of the retrobulbar optic nerve, and more frequently and later, optic nerve atrophy [4]. [Extracted from the article]