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A Peroxodiiron(III/III) Intermediate Mediating Both N‑Hydroxylation Steps in Biosynthesis of the N‑Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF.

Authors :
McBride, Molly J.
Sil, Debangsu
Ng, Tai L.
Crooke, Anne Marie
Kenney, Grace E.
Tysoe, Christina R.
Bo Zhang
Balskus, Emily P.
Boal, Amie K.
Krebs, Carsten
Bollinger Jr., J. Martin
Source :
Journal of the American Chemical Society; 7/8/2020, Vol. 142 Issue 27, p11818-11828, 11p
Publication Year :
2020

Details

Language :
English
ISSN :
00027863
Volume :
142
Issue :
27
Database :
Supplemental Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
144479303
Full Text :
https://doi.org/10.1021/jacs.0c03431