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Case report: a 10-year-old girl with primary hypoparathyroidism and systemic lupus erythematosus.

Authors :
Borysewicz-Sańczyk, Hanna
Sawicka, Beata
Michalak, Justyna
Wójtowicz, Jerzy
Dobreńko, Elżbieta
Konstantynowicz, Jerzy
Kemp, E. Helen
Thakker, Rajesh V.
Allgrove, Jeremy
Hannan, Fadil M.
Bossowski, Artur
Source :
Journal of Pediatric Endocrinology & Metabolism; Sep2020, Vol. 33 Issue 9, p1231-1235, 5p
Publication Year :
2020

Abstract

Objectives: Hypoparathyroidism is a rare disease in children that occurs as a result of autoimmune destruction of the parathyroid glands, a defect in parathyroid gland development or secondary to physical parathyroid gland disturbance. Typical symptoms of hypoparathyroidism present as hypocalcaemia and hyperphosphatemia due to decreased parathyroid hormone secretion and may lead to nerve and muscles disturbances resulting in clinical manifestation of tetany, arrhythmias and epilepsy. Currently, there is no conventional hormone replacement treatment for hypoparathyroidism and therapeutic approaches include normalising mineral levels using an oral calcium supplement and active forms of vitamin D. Case presentation: We present the case of a 10-year-old girl with primary hypoparathyroidism who had no prior history of autoimmune disorders, but who subsequently developed systemic lupus erythematosus. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0334018X
Volume :
33
Issue :
9
Database :
Supplemental Index
Journal :
Journal of Pediatric Endocrinology & Metabolism
Publication Type :
Academic Journal
Accession number :
146176310
Full Text :
https://doi.org/10.1515/jpem-2020-0015