Characteristic Comparison between Pregnant Women With and Without Preeclampsia.

Preeclampsia is still the leading cause of maternal mortality in developing countries, including Indonesia. However, there is a discrepancy between national and regional data regarding the cause of maternal death in Indonesia. National data shows that peripartum hemorrhage is the main cause of maternal death, while data from East Java region shows that the leading cause is preeclampsia. Thus, we believe that there is still lack of understanding about preeclampsia in East Java region. This study aims to scrutinize the characteristic of pregnant women with preeclampsia in East Java, Indonesia. This study was a matched case-control study conducted from June to October 2018 at secondary referral government hospitals. Variables analyzed in this study were demographic characteristic, pregnancy history, preeclampsia risk factors, and infant outcomes. Logistic regression was used to analyze preeclampsia risk factor. There were 67 preeclamptic women as case group and 67 women with normal pregnancy as control group participated in this study. Cesarean delivery was more common in case group compared to control group (59.7% vs 40.3%, p = 0.025). There were also more women in case group with familial history of preeclampsia than in control group (14.9% vs 4.5%, p = 0.041). Multivariate analysis showed that pregnant women with familial history of preeclampsia were more likely to develop preeclampsia (OR = 4.923, p = 0.036). Close monitoring to the pregnant women with familial history of preeclampsia in East Java region should be done, because they were more likely to develop preeclampsia throughout their pregnancy. [ABSTRACT FROM AUTHOR]