Knee biomechanics of patients with total knee replacement during downhill walking on different slopes.

• Replaced limb had lower knee extension moment than healthy limb in downhill walking. • Replaced limb had lower knee extension moment than non-replaced limb in downhill walking. • Knee extension moment increased across all slopes between 0° and 15° in total knee replacement patients. • Downhill walking may not be included in early stage rehabilitation after the surgery. The purpose of this study was to compare knee biomechanics of the replaced limb to the non-replaced limb of total knee replacement (TKR) patients and healthy controls during walking on level ground and on decline surfaces of 5°, 10°, and 15°. Twenty-five TKR patients and 10 healthy controls performed 5 walking trials on different decline slopes on a force platform and an instrumented ramp system. Two analyses of variance, 2 × 2 (limb × group) and 2 × 4 (limb × decline slope), were used to examine selected biomechanics variables. The replaced limb of TKR patients had lower peak loading-response and push-off knee extension moment than the non-replaced and the matched limb of healthy controls. No differences were found in loading-response and push-off knee internal abduction moments among replaced, non-replaced, and matched limb of healthy controls. The knee flexion range of motion, peak loading-response vertical ground reaction force, and peak knee extension moment increased across all slope comparisons between 0° and 15° in both the replaced and non-replaced limb of TKR patients. Downhill walking may not be appropriate to include in early stage rehabilitation exercise protocols for TKR patients. [Display omitted] [ABSTRACT FROM AUTHOR]