Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA.

Details

Language :

English

ISSN :

00222623

Volume :

64

Issue :

20

Database :

Supplemental Index

Journal :

Journal of Medicinal Chemistry

Publication Type :

Academic Journal

Accession number :

156366161

Full Text :

https://doi.org/10.1021/acs.jmedchem.1c01250