Surface modifications induced by turning on additively manufactured Zr-702 and their effects on cell adhesion and proliferation for biomedical applications.

In this paper, the analysis of surface changes and biocompatibility of Zr-702 additively manufactured bars have been performed. Samples were machined under dry and cryogenic environment at varying cutting speed and feed rate. Afterwards, MC3T3-E1 osteoblast cells were seeded on the as printed and machined surfaces verifying how cells adhesion and proliferation change based on the involved process parameters after 24 h and three days of culture. As a result, a connection between surface characteristics and process cells adhesion and proliferation has been provided and used to assess the potential of machining process to modulate biocompatibility of the investigated material. [ABSTRACT FROM AUTHOR]