How does an aging-associated enzyme access our genetic material?

Keywords: ADP Ribose Transferases; Amidohydrolases; Amino Acids; Arginine; Basic Amino Acids; Cell Nucleus Structures; Chromatin; Chromosome Structures; Chromosomes; Diamino Amino Acids; Enzymes and Coenzymes; Essential Amino Acids; Genetics; Glycosyltransferases; Group III Histone Deacetylases; Histones; Intracellular Signaling Peptides and Proteins; Intranuclear Space; Nuclear Proteins; Nucleoproteins; Nucleosomes; Penn State; Proteins; Sirtuins EN ADP Ribose Transferases Amidohydrolases Amino Acids Arginine Basic Amino Acids Cell Nucleus Structures Chromatin Chromosome Structures Chromosomes Diamino Amino Acids Enzymes and Coenzymes Essential Amino Acids Genetics Glycosyltransferases Group III Histone Deacetylases Histones Intracellular Signaling Peptides and Proteins Intranuclear Space Nuclear Proteins Nucleoproteins Nucleosomes Penn State Proteins Sirtuins 421 421 1 05/02/23 20230505 NES 230505 2023 MAY 5 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- UNIVERSITY PARK, Pa. - New research provides insight into how an enzyme that helps regulate aging and other metabolic processes accesses our genetic material to modulate gene expression within the cell. According to Tan, the nucleosome is a hundred times larger than typical histone peptides used in these studies and are consequently much more complicated to work with. "The arginine anchor is a common paradigm for how many chromatin proteins interact with the nucleosome", said Tan. [Extracted from the article]