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Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity.

Authors :
Hu, Jiantao
Hu, Biao
Xu, Fuming
Wang, Mi
Qin, Chong
McEachern, Donna
Stuckey, Jeanne
Wang, Shaomeng
Source :
Journal of Medicinal Chemistry; 6/22/2023, Vol. 66 Issue 12, p8222-8237, 16p
Publication Year :
2023

Details

Language :
English
ISSN :
00222623
Volume :
66
Issue :
12
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
164485696
Full Text :
https://doi.org/10.1021/acs.jmedchem.3c00520