Imaging findings of juvenile nasopharyngeal angiofibroma invading orbital apex and middle cranial fossa: a case report.

Background: Juvenile nasopharyngeal angiofibroma (JNA) is an infrequent, highly vascular tumor that predominantly affects male adolescents. Although benign, it rarely may exhibit invasive growth, leading to significant morbidity, as in our case presentation. Diagnosis relies on clinical evaluation and imaging, with MR and CT playing vital roles in confirming the tumor's presence, determining its extent, and aiding in treatment planning. MR shows a mass with signal voids at T2-weighted images and intense contrast enhancement at T1-weighted images, while CT shows bone remodeling and destruction. A biopsy is usually avoided due to bleeding risks. Case presentation: We present a case of a 16-year-old male with nasal obstruction and recurrent epistaxis from the right nostril, headache, and mucopurulent rhinorrhea. Furthermore, he had vision impairment in the right eye for one week associated with proptosis and periorbital swelling. MR and CT imaging evidenced the presence of JNA with extensive involvement in the nasal cavity, nasopharynx, pterygopalatine fossa, and infratemporal fossa. Moreover, the mass invaded the orbital apex and middle cranial fossa contacting the cavernous sinus and internal carotid artery. Preoperative embolization and complete surgical resection were performed. No complications occurred in the postoperative period and histopathological analysis confirmed the diagnosis of JNA. No recurrences were found at 12 months MR follow-up. Conclusions: Early detection and accurate imaging evaluation are essential for the effective management of JNA. Regular post-treatment MR follow-ups are crucial to detect recurrences or assess fibrosis stability. MR and CT continue to be indispensable tools in the diagnosis and follow-up of JNA. [ABSTRACT FROM AUTHOR]