Findings on Staphylococcus aureus Reported by Investigators at Wayne State University (Targeting Dalbavancin Inoculum Effect: Adjunctive Single Dose of Daptomycin).

Single therapies were not bactericidal when evaluated in the 168 h in vitro one-compartment model with an initial inoculum of 109; however, the combination of DAL plus single dose of DAP resulted in enhanced killing at the end of the 168-h exposure. Keywords: Detroit; State:Michigan; United States; North and Central America; Antibiotics; Antiinfectives; Bacterial Infections and Mycoses; Cyclic Peptides; Dalbavancin Therapy; Dalvance Therapy; Daptomycin Therapy; Drugs and Therapies; Glycopeptide Antibiotics; Glycopeptides Therapy; Gram-Positive Bacteria; Health and Medicine; Lipopeptides; Peptides; Pharmaceuticals; Staphylococcus aureus; Vancomycin Therapy EN Detroit State:Michigan United States North and Central America Antibiotics Antiinfectives Bacterial Infections and Mycoses Cyclic Peptides Dalbavancin Therapy Dalvance Therapy Daptomycin Therapy Drugs and Therapies Glycopeptide Antibiotics Glycopeptides Therapy Gram-Positive Bacteria Health and Medicine Lipopeptides Peptides Pharmaceuticals Staphylococcus aureus Vancomycin Therapy 1174 1174 1 11/06/23 20231110 NES 231110 2023 NOV 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Researchers detail new data in Gram-Positive Bacteria - Staphylococcus aureus. [Extracted from the article]