Study Findings from First Affiliated Hospital Advance Knowledge in Immunity Inflammation and Disease (Effect of lidocaine on cognitively impaired rats: Anti-inflammatory and antioxidant mechanisms in combination with CRMP2 antiphosphorylation).

A recent study conducted at the First Affiliated Hospital investigated the effects of lidocaine on cognitive function in rats with cognitive dysfunction. The study found that lidocaine had antioxidative stress, anti-inflammatory, and nerve-protective effects. Rats treated with lidocaine showed reduced cognitive impairment compared to the control group, and this improvement was attributed to the anti-inflammatory and antioxidative stress mechanisms of lidocaine in combination with CRMP2 antiphosphorylation. These findings suggest that lidocaine may have potential therapeutic benefits for cognitive dysfunction. [Extracted from the article]