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Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)‑2-((S)‑Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu2 Receptor Agonist.

Authors :
Liu, Na
Eshak, Floriane
Malhaire, Fanny
Brabet, Isabelle
Prézeau, Laurent
Renard, Emma
Pin, Jean-Philippe
Acher, Francine C.
Staudt, Markus
Bunch, Lennart
Source :
Journal of Medicinal Chemistry; 1/25/2024, Vol. 67 Issue 2, p1314-1326, 13p
Publication Year :
2024

Details

Language :
English
ISSN :
00222623
Volume :
67
Issue :
2
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
175028326
Full Text :
https://doi.org/10.1021/acs.jmedchem.3c01811