Investigators from University of Orebro Release New Data on Hematology (Assessing the Performance of a Targeted Absolute Quantification Isotope Dilution Liquid Chromatograhy Tandem Mass Spectrometry Assay Versus a Commercial Nontargeted...).

Researchers from the University of Orebro in Sweden have conducted a study comparing two methods for detecting polyfluoroalkyl and perfluoroalkyl substances (PFAS) in human blood. The study found that a commercial nontargeted relative quantification assay provided comparable results to the targeted absolute quantification isotope dilution LC-MS/MS assay. The two assays showed strong correlations and agreement in detecting three major PFAS. The researchers concluded that the nontargeted approach could be a valid method for studying the associations of PFAS with various health phenotypes. [Extracted from the article]