National Institute of Allergy and Infectious Diseases (NIAID) Researchers Further Understanding of RNA Vaccines (A replicating RNA vaccine confers protection in a rhesus macaque model of Crimean-Congo hemorrhagic fever).

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) have made progress in understanding RNA vaccines for Crimean-Congo hemorrhagic fever (CCHF). CCHF is a tick-borne illness with a wide geographic distribution, and currently, there are no widely available vaccines for it. The researchers used a rhesus macaque model to evaluate the immunogenicity and protective efficacy of a replicating RNA vaccine. The results showed that the vaccine induced a robust immune response and provided significant protection against CCHF in non-human primates. This research contributes to the development of potential vaccines for CCHF. [Extracted from the article]