Data from Central University of Gujarat Update Knowledge in Drug Design and Development (Experimental and computational characterization of p-Sulfocalix[4]arene mediated delivery system for morin hydrate).

A recent report from the Central University of Gujarat in India discusses the use of p-Sulfocalix[4]arene as a complexing agent to improve the solubility and stability of the drug morin hydrate. The researchers used various techniques to analyze the inclusion complex between morin hydrate and p-Sulfocalix[4]arene, and found that it significantly enhanced the solubility of morin hydrate. The complex also showed increased anticancer activity compared to native morin hydrate. The researchers concluded that the designed complex could be a promising drug delivery carrier for hydrophobic morin hydrate. [Extracted from the article]