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Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding Rapidly Characterize the Structural Polydispersity and Stability of an Fc-Fusion Protein.

Authors :
Villafuerte-Vega, Rosendo C.
Li, Henry W.
Bergman, Addison E.
Slaney, Thomas R.
Chennamsetty, Naresh
Chen, Guodong
Tao, Li
Ruotolo, Brandon T.
Source :
Analytical Chemistry; 6/18/2024, Vol. 96 Issue 24, p10003-10012, 10p
Publication Year :
2024

Details

Language :
English
ISSN :
00032700
Volume :
96
Issue :
24
Database :
Supplemental Index
Journal :
Analytical Chemistry
Publication Type :
Academic Journal
Accession number :
177960906
Full Text :
https://doi.org/10.1021/acs.analchem.4c01408