"Efficient Biocompatible Cryopreservation Medium That Eliminates The Need For Cell Permeating Cryoprotectants" in Patent Application Approval Process (USPTO 20240180148).

A patent application has been filed for an efficient cryopreservation medium that eliminates the need for cell permeating cryoprotectants. Cryopreservation is the technique of storing biological materials at temperatures below freezing, but current methods rely on small molecule cryoprotectants that can cause issues. The new cryopreservation medium includes hydrophilic particles or macromolecules that form nano scale cubic ice around the lipid membrane of biological structures, protecting them during freezing. This innovation could improve the viability and functionality of cells and tissues after thawing, benefiting fields such as tissue engineering and regenerative medicine. [Extracted from the article]