New Hormones Findings from University of Alabama Birmingham Reported (Unveiling Ceramide Dynamics: Shedding Light On Healthy Aging In Growth Hormone-releasing Hormone Knockout Mice).

A recent study conducted at the University of Alabama Birmingham explored the effects of growth hormone deficiency on aging and longevity. The researchers analyzed serum samples and liver tissue from growth hormone-releasing hormone knockout mice, a model for enhanced longevity. They found that older mice exhibited significant reductions in ceramide levels, which are associated with aging-related tissue defects. The study provides evidence of disrupted ceramide metabolism in long-lived mammals and sheds light on the connection between growth hormone deficiency, ceramide levels, and lifespan extension. The research was supported by the National Institutes of Health. [Extracted from the article]