University of Petra Researcher Updates Current Data on Antidiabetic Agents (Genetic analysis: therapeutic drug monitoring of metformin and glimepiride on diabetic patients' plasma including genetic polymorphism).

A recent study conducted by researchers at the University of Petra in Amman, Jordan, explored the correlation between the blood levels of metformin and glimepiride, two antidiabetic agents, and genetic polymorphism in diabetic patients. The study involved 106 patients with type 2 diabetes and found that patients with a specific genetic polymorphism had higher levels of metformin in their blood. The researchers suggest that genotype-guided drug therapy could potentially enhance drug efficacy and minimize toxicity. This research provides valuable insights into the therapeutic monitoring of antidiabetic agents and their impact on diabetic patients. [Extracted from the article]