A Prospective, Multicenter, Observational Pilot Study to Evaluate the Combination of niPGT-A and Morphokinetics for the Non-invasive Assessment of Embryo Development.

This article discusses a clinical trial, NCT06524648, that is investigating the use of non-invasive techniques to assess embryo development in in vitro fertilization (IVF). The traditional method of evaluating embryos based on appearance and genetic testing has limitations, and new techniques that do not require manipulation of the embryo are being explored. The trial will involve infertile women undergoing IVF/ICSI treatment with non-invasive Preimplantation Genetic Testing for Aneuploidies (niPGT-A). The main objective is to identify parameters during embryo development that may be related to the embryo's chromosomal status. The trial will also examine correlations between morphokinetic parameters and outcomes such as implantation rate, clinical pregnancy rate, and live birth rate. The study aims to improve embryo evaluation and reproductive outcomes in IVF treatments. [Extracted from the article]