Data on Science and Technology Reported by Researchers at Hunan University of Chinese Medicine (TMAO is involved in kidney-yang deficiency syndrome diarrhea by mediating the "gut-kidney axis").

A study conducted by researchers at Hunan University of Chinese Medicine in China has found that Trimethylamine-N-oxide (TMAO), a harmful metabolite, is involved in kidney-yang deficiency syndrome diarrhea by mediating the "gut-kidney axis." The researchers used a mouse model to investigate the microbiological causes of this syndrome and found that TMAO is associated with increased inflammation and cytokines, as well as disruptions in the intestinal barrier and renal fibrosis. The study suggests that dysfunction of the "gut-kidney axis" can lead to elevated TMAO levels, perpetuating a vicious cycle. [Extracted from the article]