Research Results from Autonomous University Barcelona Update Understanding of Parkinson's Disease (Impact of Stimulation Frequency on Verbal Fluency Following Bilateral Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease).

A recent study conducted at Autonomous University Barcelona examined the impact of stimulation frequency on verbal fluency in patients with Parkinson's disease who underwent deep brain stimulation (DBS) in the subthalamic nucleus (STN). The study included 38 patients with Parkinson's disease who received either low frequency STN-DBS (LFS) or high frequency STN-DBS (HFS), as well as a control group of non-operated patients. The results showed that HFS negatively affected letter, semantic, and action fluencies, while LFS had no effect on verbal fluency. However, the decline in verbal fluency following STN-DBS was not solely caused by stimulation frequency. This research provides valuable insights into the effects of DBS on verbal fluency in Parkinson's disease patients. [Extracted from the article]