Findings from Sun Yat-sen University Yields New Data on Retinitis Pigmentosa (Minocycline Prevents Photoreceptor Degeneration In Retinitis Pigmentosa Through Modulating Mitochondrial Homeostasis).

A study conducted by researchers at Sun Yat-sen University in Guangzhou, China, has found that minocycline, a broad-spectrum tetracycline antibiotic, may have potential in treating retinitis pigmentosa (RP). The study showed that minocycline therapy effectively restored retinal function and structure in mice with RP, and inhibited the activation of microglia. The researchers also found that minocycline modulated mitochondrial homeostasis, reducing levels of mitochondrial reactive oxygen species and providing protection against photoreceptor degeneration. These findings have significant implications for the development of potential therapeutic strategies for RP. [Extracted from the article]