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New Listeria monocytogenes Data Have Been Reported by Investigators at University of Jinan (Ulk1 Regulates T Cell Development and Response To Listeria Monocytogenes Stimulation).

Source :
Genomics & Genetics Weekly; 10/4/2024, p618-618, 1p
Publication Year :
2024

Abstract

Researchers at the University of Jinan in Guangzhou, China have discovered that a protein called ULK1 plays a crucial role in regulating the development and function of T cells, which are important for the immune system. The absence of ULK1 leads to an increase in a specific type of cell in the thymus and a reduction in the number of T cells in peripheral immune organs. Additionally, mice lacking ULK1 have a weaker ability to clear Listeria infection and their T cells have defects in producing cytokines. The study suggests that ULK1 is essential for T-cell maturation, maintaining the balance of peripheral T cells, and their functional response to antigens. [Extracted from the article]

Details

Language :
English
ISSN :
15316467
Database :
Supplemental Index
Journal :
Genomics & Genetics Weekly
Publication Type :
Periodical
Accession number :
179936823