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Discovery of CZL-046 with an (S)‑3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma.

Authors :
Chen, Zonglong
Yang, Hong
Zhang, Yan
Lyu, Xiaodong
Shi, Qiongyu
Zhang, Cheng
Wang, Xingcan
Wang, Zekun
Zhang, Ying
Deng, Yue
Wang, Yujie
Huang, Yuting
Xu, Yong
Huang, Xun
Li, Yingxia
Source :
Journal of Medicinal Chemistry; 10/24/2024, Vol. 67 Issue 20, p18606-18628, 23p
Publication Year :
2024

Details

Language :
English
ISSN :
00222623
Volume :
67
Issue :
20
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
180485465
Full Text :
https://doi.org/10.1021/acs.jmedchem.4c01984