Research from University Indonesia in the Area of Collagen Diseases and Conditions Described (Efficient Protocol for Isolating Human Fibroblast from Primary Skin Cell Cultures; Application to Keloid, Hypertrophic Scar and Normal Skin Biopsies).

Researchers from the University Indonesia have developed an efficient protocol for isolating human fibroblasts from skin cell cultures, focusing on applications to keloid, hypertrophic scar, and normal skin biopsies. The method involves derivation, culture, and characterization analysis, showing high amounts of fibroblasts with in vivo-like characteristics. Fibroblasts derived from keloid tissue exhibited the highest rate of proliferation and migration, suggesting a reproducible technique for studying fibrotic dermatological disorders in vitro. This research provides a foundation for further investigations into potential interventions for aberrant fibrotic conditions. [Extracted from the article]