Collagen binding adhesin restricts Staphylococcus aureus skin infection.

The article discusses the impact of a collagen binding adhesin on Staphylococcus aureus skin infections. Staphylococcus aureus is a common cause of skin infections, and the adhesin Cna plays a crucial role in infection severity and bacterial clearance. The inability of S. aureus to bind collagen leads to worsened pathology, while binding to collagen-like domains reduces opsonophagocytic functions. This research sheds light on the complex interactions between bacteria, host proteins, and immune responses during skin infections. [Extracted from the article]