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HMGCR antibody-associated myopathy in patient with endometrial cancer: a rare case.

Authors :
Wada, T.
Hashiguchi, Y.
Kasai, M.
Fukuda, T.
Ichimura, T.
Yasui, T.
Sumi, T.
Source :
European Journal of Gynaecological Oncology; 2020, Vol. 41 Issue 1, p148-150, 3p
Publication Year :
2020

Abstract

Background: Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody (HMGCR antibody) antibody-associated myopathy is a rare disease. HMGCR antibody-associated myopathy in patient with endometrial cancer is extremely rare. Case Report: A 60-year-old woman without statin exposure presented with endometrial cancer Stage IIIC1 (T2N1M0) and HMGCR antibody-associated myopathy. After diagnosis, the patient received chemotherapy combining paclitaxel and carboplatin for endometrial cancer, and steroid and immunoglobulin for HMGCR antibody-associated myopathy. Two months after two cycles of chemotherapy, she died. Autopsy revealed that she died of HMGCR antibody-associated myopathy. Conclusion: In case of myopathy in patients with endometrial cancer, HMGCR antibody-associated myopathy should be considered. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03922936
Volume :
41
Issue :
1
Database :
Supplemental Index
Journal :
European Journal of Gynaecological Oncology
Publication Type :
Academic Journal
Accession number :
181269463
Full Text :
https://doi.org/10.31083/j.ejgo.2020.01.4901