New Knee Osteoarthritis Study Findings Have Been Reported by a Researcher at Sichuan University (EZH2/miR-142-3p/HMGB1 axis mediates chondrocyte pyroptosis by regulating endoplasmic reticulum stress in knee osteoarthritis).

A recent study conducted at Sichuan University in China explored the role of endoplasmic reticulum stress in chondrocyte pyroptosis in knee osteoarthritis (OA). The research identified an EZH2/miR-142-3p/HMGB1 axis that regulates chondrocyte pyroptosis and cartilage degeneration in OA. These findings offer new insights into the pathogenesis of OA and potential therapeutic targets for future research. [Extracted from the article]