Study Findings from Friedrich-Alexander-University Erlangen-Nurnberg (FAU) Advance Knowledge in Myositis (Exploring CAR T-Cell Dynamics: Balancing Potent Cytotoxicity and Controlled Inflammation in CAR T-Cells Derived from Systemic Sclerosis...).

A recent study conducted at Friedrich-Alexander-University Erlangen-Nurnberg (FAU) explored the dynamics of CAR T-cells in patients with systemic sclerosis and myositis. The research focused on Hu19-CD828Z, a CAR T-cell therapy designed to deplete B-cells, showing promising results in vitro. The study suggests that this therapy could be a potential treatment strategy for autoimmune diseases like systemic lupus erythematosus, idiopathic inflammatory myositis, and systemic sclerosis. For more information, the full article can be accessed for free at the International Journal of Molecular Sciences website. [Extracted from the article]