Researchers from University of Sheffield Describe Research in Breast Cancer (Efficient and Rapid Microfluidics Production of Bio-Inspired Nanoparticles Derived from Bombyx mori Silkworm for Enhanced Breast Cancer Treatment).

Researchers from the University of Sheffield have developed a method to efficiently produce silk fibroin particles (SFPs) using a swirl mixer for potential use in breast cancer treatment. The SFPs showed promising characteristics for drug delivery, including encapsulation of curcumin and 5-fluorouracil with sustained release profiles. In vitro and in vivo studies demonstrated effective drug delivery to breast cancer cells with minimal toxicity to non-cancerous cells, highlighting the potential of this approach for targeted cancer therapy. This research contributes to the advancement of therapeutic strategies in breast cancer treatment through the use of bio-inspired nanoparticles derived from Bombyx mori silkworm. [Extracted from the article]