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Hereditary Fructose Intolerance and Celiac Disease: A Novel Genetic Association.
- Source :
- Clinical Gastroenterology & Hepatology; May2006, Vol. 4 Issue 5, p635-638, 4p
- Publication Year :
- 2006
-
Abstract
- Background & Aims: Celiac disease (CD) has been associated with several genetic disorders, but has not been associated with hereditary fructose intolerance (HFI). Methods: We identified CD in 4 female patients affected by HFI from among 38 Italian HFI patients. Results: Three of these patients were children in whom the CD-associated signs were hypertransaminasemia, failure to thrive, low weight, and short stature, whereas the adult patient had protracted diarrhea notwithstanding a fructose-free diet. The incidence of CD in our group of HFI patients was higher (>10%) than in the general population (1%–3%) (P < .02). Conclusions: The possibility of an association between these 2 gastrointestinal disorders is important, particularly in the management of HFI patients with persisting symptoms. [Copyright &y& Elsevier]
- Subjects :
- ASSOCIATIONS, institutions, etc.
DIARRHEA
GENETIC disorders
INTESTINAL diseases
Subjects
Details
- Language :
- English
- ISSN :
- 15423565
- Volume :
- 4
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Clinical Gastroenterology & Hepatology
- Publication Type :
- Academic Journal
- Accession number :
- 22408055
- Full Text :
- https://doi.org/10.1016/j.cgh.2005.12.004