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Analise estatistica baseada em voxel do SPECT ictal revela um padrao de alteracao perfusional em pacientes com epilepsia de lobo temporal.
- Source :
- Arquivos de Neuro-Psiquiatria; Dez2005, Vol. 63 Issue 4, p5-5, 1p
- Publication Year :
- 2005
-
Abstract
- OBJECTIVE: To investigate the pattern of perfusion abnormalities in ictal and interictal brain perfusion SPECT images (BSI) from patients with temporal lobe epilepsy (TLE). METHOD: It was acquired interictal and ictal BSI from 24 patients with refractory TLE. BSIs were analyzed by visual inspection and statistical parametric mapping (SPM2). Statistical analysis compared the patients group to a control group of 50 volunteers. The images from patients with left-TLE were left-right flipped. RESULTS: It was not observed significant perfusional differences in interictal scans with SPM. Ictal BSI in SPM analysis revealed hyperperfusion within ipsilateral temporal lobe (epileptogenic focus) and also contralateral parieto-occipital region, ipsilateral posterior cingulate gyrus, occipital lobes and ipsilateral basal ganglia. Ictal BSI also showed areas of hypoperfusion. CONCLUSION: In a group analysis of ictal BSI of patients with TLE, voxel-wise analysis detects a network of distant regions of perfusional alteration which may play active role in seizure genesis and propagation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0004282X
- Volume :
- 63
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Arquivos de Neuro-Psiquiatria
- Publication Type :
- Academic Journal
- Accession number :
- 23641171